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技术规格
Background:
Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Applications:
WB
Name of antibody:
SHB
Immunogen:
Synthesized peptide derived from C-terminal of human SHB.
Full name:
Src homology 2 domain containing adaptor protein B
Synonyms:
bA3J10.2
SwissProt:
Q15464
WB Predicted band size:
55 kDa
WB Positive control:
Huvec cells lysate
WB Recommended dilution:
500-3000