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技术规格
Background:
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Applications:
ELISA, IHC
Name of antibody:
SCN2A
Immunogen:
Synthetic peptide of human SCN2A
Full name:
sodium channel, voltage-gated, type II, alpha subunit
Synonyms:
HBA; NAC2; BFIC3; BFIS3; BFNIS; HBSCI; EIEE11; HBSCII; Nav1.2; SCN2A1; SCN2A2; Na(v)1.2
SwissProt:
Q99250
ELISA Recommended dilution:
1000-5000
IHC positive control:
Human ovarian cancer
IHC Recommend dilution:
25-100