兔抗RFX6多克隆抗体

Background:

The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.

Applications:

ELISA, IHC

Name of antibody:

RFX6

Immunogen:

Fusion protein of human RFX6

Full name:

regulatory factor X6

Synonyms:

MTFS; MTCHRS; RFXDC1; dJ955L16.1

SwissProt:

Q8HWS3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-300