兔抗QDPR多克隆抗体

Background:

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Applications:

ELISA, WB, IHC

Name of antibody:

QDPR

Immunogen:

Fusion protein of human QDPR

Full name:

quinoid dihydropteridine reductase

Synonyms:

DHPR; PKU2; HDHPR; SDR33C1

SwissProt:

P09417

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human ovarian cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

26 kDa

WB Positive control:

Mouse liver tissue, Mouse brain tissue, Rat brain tissue, Rat liver tissue and Human fetal liver tissue lysates

WB Recommended dilution:

500-2000