手机扫码访问本站


微信咨询

[JN7651]小鼠抗GAPDH单克隆抗体

价格:0

货号:JN7651

规格: 200ul 25ul 100ul

联系方式:021-54479081

立即购买 说明书下载

买家导航

中文名称:  小鼠抗GAPDH单克隆抗体 

英文名称: Anti-GAPDH mouse monoclonal antibody

相关类别: 内参抗体

储       存: 冷冻(-20℃) 避光

宿       主: Mouse

抗        原: GAPDH

反应种属: Human, Mouse, Rat

标  记  物: Unconjugate

克隆类型: mouse monoclonal

技术规格


Background:

This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.

Applications:

WB, IHC

Name of antibody:

GAPDH

Immunogen:

Fusion protein of human GAPDH

Full name:

glyceraldehyde-3-phosphate dehydrogenase

Synonyms:

G3PD; GAPD; HEL-S-162eP

SwissProt:

P04406

IHC positive control:

Human ovarian cancer and Human breast cancer; Human esophagus cancer and Human lung cancer

IHC Recommend dilution:

250-1000

WB Predicted band size:

36 kDa

WB Positive control:

Mouse brain tissue, Rat brain tissue, Human cerebrum tissue, Human cerebella tissue, PC-3 cell, Jurkat cell, HepG2 cell, Mouse skeletal muscle tissue lysates

WB Recommended dilution:

1000-5000







检测试剂盒分类