手机扫码访问本站
微信咨询
中文名称： EGF 抗原（重组蛋白）
英文名称： EGF Antigen (Recombinant Protein)
别 名： epidermal growth factor; URG, HOMG4
相关类别： 抗原
储 存 ：冷冻（-20℃）
概述
|
Fusion protein corresponding to a region derived from 926-1026 amino acids of human EGF |
技术规格
|
Full name: |
epidermal growth factor |
|
Synonyms: |
URG, HOMG4 |
|
Swissprot: |
P01133 |
|
Gene Accession: |
BC113461 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants |
