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DTX3L抗原(重组蛋白)

品牌:纪宁生物

货号:JN7235

规格: 1mg 100ug

联系方式:021-66980655

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产品详情

中文名称:DTX3L抗原(重组蛋白)


英文名称: DTX3L Antigen (Recombinant Protein)


储  存: 冷冻(-20℃)


相关类别: 抗原


概述

Fusion protein corresponding to a region derived from 441-740 amino acids of human DTX3L


技术规格

Full name:

deltex E3 ubiquitin ligase 3L

Synonyms:

BBAP

Swissprot:

Q8TDB6

Gene Accession:

BC042191

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The Deltex family is responsible for influencing Notch signaling and may regulate transcription through interactions with specific transcription factors. Deltex proteins have a basic N-terminus, a central proline-rich region and a C-terminal RING-type zinc finger domain, a motif often found in ubiquitin-protein isopeptide ligases (E3). The RING-type zinc finger domain binds two Zn2+ atoms and forms a cross-brace motif that is essential for many proteins involved the ubiquitination pathway. DTX3L (Deltex-3-like), also known as BBAP, is a 740 amino acid protein that is similar to Deltex-3 and acts as a ubiquitin ligase in vitro. DTX3L can heterodimerize with Deltex-1, a transcriptional regulator, thereby enhancing the activity of the E3 ubiquitin ligase complex and increasing the influence of E3 on the Notch signaling pathway.

友情链接:
elisa试剂盒 elisa检测试剂盒 elisakit 植物elisa试剂盒 CAS号数据库
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