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[JN626]兔抗MDM2多克隆抗体

价格:0

货号:JN626

规格: 100ul 200ul 25ul

联系方式:021-54479081

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中文名称: 兔抗MDM2多克隆抗体


英文名称: Anti-MDM2 rabbit polyclonal antibody


别       名: HDMX; hdm2; ACTFS


相关类别: 一抗


储      存: 冷冻(-20℃) 避光


宿      主: Rabbit


抗      原: MDM2


反应种属: Human


标  记  物: Unconjugate


克隆类型: rabbit polyclonal


技术规格


Background:

MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 . Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53 . Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53 .

Applications:

WB

Name of antibody:

MDM2

Immunogen:

Synthetic peptide of human MDM2

Full name:

MDM2 oncogene, E3 ubiquitin protein ligase

Synonyms:

HDMX; hdm2; ACTFS

SwissProt:

Q00987

WB Predicted band size:

90 kDa

WB Positive control:

293 and Hela cells

WB Recommended dilution:

500-1000



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